Parents with dogs who suffer from osteoarthritis know how frustrating it is to see your dog struggle with mobility. We can move mountains just to see our furry friend lively and jumping up and down again. One of the most recommended drugs for dogs with joint pain and mobility issues is Galliprant. If you gave your dog this vet-prescribed drug to your dog but you are now blaming it for the death of your beloved pet, this article is for you and I am very sorry for your loss.
In this article, we will discuss everything about Galliprant, its side effects, dosage, how to administer it, and most importantly, give you some of the instances that can lead to the death of a dog after taking Galliprant.
What is Galliprant®? (grapiprant)
Galliprant is a brand name for the drug grapiprant, a nonsteroidal anti-inflammatory drug (NSAID) used in dogs to manage the pain and inflammation associated with osteoarthritis. Available in a flavored, chewable tablet, Galliprant can be used for daily long-term treatment, starting from the early stages of canine arthritis. Although osteoarthritis commonly affects older dogs, Galliprant is approved for use in young dogs that are 9 months or older and weigh more than 8 pounds. Galliprant is a prescription medication, and it is usually administered as a pill or chewable tablet. It should only be used under the supervision of a veterinarian.
How Galliprant® Works
NSAIDs work by suppressing prostaglandin. Prostaglandins are a group of chemicals that the body releases at sites of inflammation, tissue damage, and infection. However, the effects of prostaglandins can cause several side effects including constriction of blood vessels, contraction of smooth muscles in the digestive system, and the formation of blood clots.
Galliprant® does not suppress prostaglandins but instead blocks a prostaglandin receptor which is involved in generating pain and inflammation. By not suppressing prostaglandins, blood clotting, constriction of blood vessels, and contraction muscles of the digestive system are not impacted.
How Is Grapiprant Given?
Grapiprant is administered orally as a pill. It can be taken with or without meals, however, absorption is better when taken on an empty stomach. If vomiting happens when taken on an empty stomach, administer it with food or a treat the next time.
This medication will take effect fast, within 1 to 2 hours, and clinical symptoms should improve.
Galliprant Killed My Dog
Below are some reasons why a dog can die after taking Galiiprant. However, it is crucial to note that the danger of fatal results is relatively minimal when taken according to your veterinarian’s instructions.
Allergic Reactions: Although rare, some dogs may experience allergic reactions to Galliprant. These responses can range in intensity from mild to severe and can include symptoms including hives (itchy raised welts on the skin), swelling (particularly of the face, lips, or tongue), difficulty breathing, coughing, or sneezing. Anaphylaxis, a severe allergic reaction, can be life-threatening and needs rapid veterinary care. When giving their dog a new medication like Galliprant, pet owners must be watchful for any indications of an allergic reaction.
Gastrointestinal Issues: Galliprant, like other NSAIDs, might irritate a dog’s digestive tract’s lining. This inflammation occasionally causes gastrointestinal bleeding, vomiting, or diarrhea as adverse effects. Long-lasting or serious digestive problems can lead to electrolyte imbalances, dehydration, and weight loss. If this problem is not attended to fast, it can lead to death.
Underlying health condition: NSAIDs, including Galliprant, have the potential to have an impact on kidney and liver function, especially in dogs that already have kidney or liver issues. These drugs may reduce blood filtration and interfere with blood flow to these organs, which could result in problems including liver toxicity or kidney damage. Blood tests are a vital part of monitoring your dog’s kidney and liver function, especially if they have a history of kidney or liver disorders. This allows you to identify any possible problems early and change your dog’s therapy as needed.
Overdose: Overdosing on Galliprant can cause serious negative effects if done without a vet’s approval. Lethargy (severe exhaustion), weakness, loss of appetite, and even unconsciousness are all possible overdose symptoms. If left unattended, overdosing can easily lead to death.
Drug interaction: Galliprant could interact with other drugs your dog is currently on. The effectiveness of one or more medications may be increased or decreased as a result of these interactions, potentially creating complications that can be fatal. To be sure there are no negative interactions, let your vet know about all prescription and over-the-counter medications, dietary supplements, and herbal therapies that your dog is currently taking. If necessary, your veterinarian can assist in modifying the treatment plan or drug dosages.
How long does Galliprant take to start working?
Galliprant’s effects normally begin to manifest within 1 to 2 hours. However, it is difficult to estimate when you will notice any significant improvement in your dog’s condition. Some dogs’ symptoms may improve within a few days, while others may take many weeks to respond to the drug properly.
When Should A Dog Stop Taking Galliprant?
The length of treatment with Galliprant for dogs can vary based on several factors. Some of the factors include the illnesses, the dog’s age, and any additional drugs your dog may be taking concurrently.
Canine osteoarthritis is a chronic ailment that needs to be followed up on and managed by your vet. Galliprant is frequently prescribed as a long-term pain reliever so that your dog can continue to lead an active and fulfilling life.
Your dog’s demands and reaction to treatment will be taken into consideration by your veterinarian when deciding how long exactly your dog will be on Galliprant.
Regular check-ups and consultations with your veterinarian will ensure that the medication is working properly and that your dog’s condition is being handled appropriately over time.
Galliprant’s Potential Side Effects
While Galliprant has been demonstrated to be beneficial in reducing joint pain and inflammation, there may be some negative effects. As with any medication, your dog’s reaction will be determined by a variety of factors, including their overall health, age, and size.
Problems with the Digestive System
The most often reported side effect of Galliprant is gastrointestinal problems, which can appear as vomiting, diarrhea, or appetite changes. If your dog experiences these problems, you should consult your vet so you can administer the drug after meals.
Behavioral changes
Following the use of Galliprant, some dog owners have noted behavioral changes in their pets. These could be more panting, trembling, or lethargic behavior. If your dog exhibits major changes in behavior or energy, it would be wise to talk to your veterinarian.
Allergic Reactions
Although rare, adverse reactions can happen when taking any drug. The signs of an allergic reaction include hives, breathing issues, or swelling of the face, lips, tongue, or throat. Call your vet immediately if you think you could be having an allergic reaction.
Liver and Kidney Health
Galliprant is metabolized by the liver and kidneys like many other NSAIDs. Galliprant may not be the best option if your pet has liver or kidney illness. Regular blood tests will likely be done by your veterinarian to check on your dog’s liver and kidney health while they are taking the medicine.
What is the Dosage of Galliprant for Dogs?
Before deciding on the dosage, your vet will evaluate numerous important criteria such as your dog’s weight, age, overall health, and specific health condition.
Galliprant is prescribed for dogs at a dose of 0.9 mg per pound (2mg/kg) of body weight once daily. It is always best to administer the lowest effective dose for the shortest possible time, although there are exceptions.
Galliprant chews come in three strengths: 20 mg, 60 mg, and 100 mg tablets. The 20 and 60 mg tablets are scored and easily breakable for easy calculation in half-tablet increments. The 100 mg pills, on the other hand, are not scored and must not be crushed or broken.
As your dog heals, the dosage may need to be adjusted, which your vet will decide later.
Stick to their instructions and never give your dog a higher or more frequent dose than advised, since this can have negative consequences.
Below is a Dosage recommendations table:
| Dog’s Weight | Starting Dosage (Once Daily) | Maximum Dosage (Once Daily) |
| 5 kg (11 lbs) | 10 mg | 15 mg |
| 10 kg (22 lbs) | 20 mg | 30 mg |
| 20 kg (44 lbs) | 40 mg | 60 mg |
Which Dogs Should Not Take Galliprant?
Although Galliprant is typically safe and effective, it is not appropriate for all dogs. This drug should not be used in the following situations:
- Canines who are allergic or sensitive to the active ingredient
- Dogs who are sensitive to sulfonamide medications
- Dogs who are sensitive to or allergic to pork proteins
- Dogs suffering from heart illness
- Puppies under nine months old
- Dogs weighing less than 3.6 kg (8 pounds)
- Dogs that are breeding, pregnant, or nursing
Galliprant should, however, be used with extreme caution and under strict observation in the following situations:
- Very dehydrated dogs
- Dogs with pre-existing liver, renal, and GI disorders
Galliprant Alternative For Dogs
There are additional alternatives for helping dogs manage pain and inflammation, and seeing your vet is the best way to understand which one is best for your pet.
They will assess your dog’s needs and health condition before recommending the best solution.
NSAIDs – Galliprant can be replaced with other NSAIDs. Rimadyl, Metacam, Deramaxx, Previcox, and Onsior, for example, can all be used to alleviate inflammation. Again, your veterinarian will check blood levels before and after use to ensure no kidney or liver damage occurs.
Gabapentin for dogs– Gabapentin is an anticonvulsant medication used to treat anxiety, pain, and seizures in dogs.
Companion Therapy Laser– The Companion Therapy Laser is a Class IV deep tissue laser that uses strong light particles to deeply enter tissue and stimulate cells to repair.
Supplements – Another alternate therapy option for Galliprant is nutritional supplementation. Omega-3 fatty acids, for example, are known to promote joint mobility. Glucosamine and chondroitin are two other supplements to consider instead of Galliprant.
CBD oil for dogs – Cannabinoids, particularly CBD, showed they can exhibit analgesic and anti-inflammatory effects in several inflammatory-induced chronic pain models. Barbara Costa of the University of Milano-Bicocca’s Department of Biotechnology and Bioscience conducted research and discovered that CBD has significant anti-inflammatory benefits.
CBD’s anti-inflammatory effects may help your dog naturally combat joint pain, stiffness, and swelling, allowing your best buddy to live with less discomfort.
Weight management
Maintaining a healthy weight is essential for dogs suffering from arthritis.
Extra pounds, as you might expect, will put greater strain on their joints and aggravate their pain.
For the best diet and exercise regimen for your dog, I recommend consulting with your veterinarian or a dog nutritionist. Discover the ideal balance for your dog’s body!
FAQs
Can humans take Galliprant to treat joint pain and arthritis?
Galliprant is a medication made specifically for dogs. Under no circumstances should a person take Galliprant. Contact your doctor if you are experiencing joint discomfort or arthritis.
What should I do if I forget to give my dog a dose of Galliprant?
Give your dog their next dosage of Galliprant as soon as possible. If you’ve left it for more than 2 hours or your dog is due for their next dose, skip the missed one. Do not double up on Galliprant dosages as this may result in an overdose or serious negative effects.
How Long Will Gabapentin Stay in My Dog’s System?
Gabapentin often remains in your dog’s system for 48 to 72 hours after the last dose. It does, however, frequently take up to 4-5 days to be totally eliminated.
Because the liver is involved in gabapentin metabolism, dogs with liver disorders may have a longer elimination time.
As a result, it is critical to strictly adhere to your veterinarian’s instructions and only administer gabapentin as directed.
If you have any concerns about potential adverse side effects or drug interactions, always check with your veterinarian to acquire additional information and ensure your dog’s safety and health.
Does Galliprant Cause Panting in Dogs?
Galliprant does not often cause panting, thus the fact that your dog is panting or pacing may just be a coincidence.
It was only recently approved in 2018, so it’s important to keep an eye out for any unusual behavior in your dog. Visit a veterinarian right away and let them know if your dog is excessively pacing or panting.
If there are any problems with the present dosage of the Galliprant or if changes need to be made to the drug schedule, they will let you know.
Do I need to monitor my dog?
Yes. When giving Galliprant to your dog for the first time, keep an eye on him. Consult your veterinarian; they might suggest adjusting the dose if you detect changes in the stool or vomiting in your pet. However, there usually isn’t a requirement for continuous monitoring outside of routine care if you give your dog several doses of Galliprant and they suffer no problems.
Information on Galliprant® Overdose
The most typical indicators of a Galliprant® overdose include vomiting, loss of appetite, and changes in the stool (diarrhea, soft stool, or mucous stool). Blood protein levels are reduced and liver-related enzymes are elevated, especially with chronic overdose.
If you suspect an overdose, contact your veterinarian or an animal poison control center right away.
Galliprant® Storage
Galliprant® should be stored in a temperature-controlled room at or below 86°F. Keep the container tightly closed to keep moisture and light out. Always double-check storage requirements by reading the label.
Keep children and pets out of reach.
Galliprant® make a dog sleepy?
Dogs do not normally become sleepy while taking Galliprant®, although they may feel more exhausted and appear less lively than usual. Please notify your veterinarian right away if you observe that your pet is sleeping more than usual while on this medicine.
