Deramaxx Killed My Dog

To treat pain and inflammation in dogs, veterinarians frequently prescribe the drug Deramaxx. However, it can have negative effects that could hurt your pet, just like any medication. But can Deramaxx kill a dog? This article will answer this question and provide you with the information you need to make an informed choice on the use of this medication for your dog.

What is Deramaxx®?

Deramaxx® (deracoxib) is a non-narcotic, non-steroidal anti-inflammatory (NSAID) prescription drug for dogs that has received FDA approval. It is mostly used to relieve pain and inflammation that develop after orthopedic and general surgeries, including dental surgery. It can also be used to reduce fevers and inflammation brought on by other diseases. It is also used to treat arthritis-related inflammation. 

Through off-label use, Deramaxx® may have some anti-cancer effects in dogs. It can be used in conjunction with some chemotherapy drugs to treat some types of bladder cancer called transitional cell carcinoma (TCC) and hemangiosarcoma, which are blood-based cancers.

How Deramaxx® Works

NSAIDs inhibit the COX pathway, a set of naturally occurring molecules that cause inflammation. Some COX pathways are advantageous for digestion, kidney health, and coagulation, however, Deramaxx® inhibits far more inflammatory chemicals than advantageous ones. The beneficial compounds can still be somewhat inhibited by Deramaxx®, especially at larger doses, so be sure to discuss the prescription instructions with your veterinarian and carefully follow them.

Deramaxx Killed My Dog

Below are some of the reasons why a dog can die after taking Deramaxx;


Overdosing or administering Deramaxx at an inappropriate dosage is one of the most frequent ways that it might hurt your dog. Giving your dog too much of the drug might have serious side effects including death, lethargy, vomiting, diarrhea, and seizures. On the other side, if you give your dog too little of the medication, their pain and inflammation may not be adequately controlled.

Allergic Reactions

Deramaxx may occasionally cause an allergic response in dogs. Hives, swelling, breathing difficulties, and collapse are all indications of an allergic reaction. Go to the vet immediately if you sense your dog is having an allergic response to Deramaxx.

Drug interactions with other drugs

Other medications your dog is taking, including over-the-counter vitamins and herbal therapies, may interact with Deramaxx. To prevent potential problems, always let your veterinarian know about any drugs or supplements your dog is taking.

Previously Existing Conditions

Your dog may be more vulnerable to the negative effects of Deramaxx if they already have health issues. Most susceptible are dogs with renal or liver disease, gastrointestinal issues, or heart disease. Before giving your dog Deramaxx let your veterinarian know if there are any underlying medical conditions.

Breed and Age

Your dog’s tolerance to Deramaxx may also depend on their breed and age. Certain breeds, such as Greyhounds and Collies, may be more sensitive to the medicine’s effects, while older dogs may have a harder time absorbing the medication. Based on your dog’s age and breed, your veterinarian can assist establish whether Deramaxx is safe for him or her.

How Long Can a Dog Stay on Deramaxx?

The severity of the dog’s condition and the veterinarian’s advice will determine how long Deramaxx is administered. Deramaxx is often administered for a brief term for acute pain, such as post-operative discomfort. Dogs may need to take the drug for a long time, though, if they have a chronic ailment like arthritis. Always talk to your vet about your dog’s recommended course of therapy.

How should I administer Deramaxx to my dog?

Deramaxx comes in chewable tablet form and can be taken with or without food. To maintain consistent drug levels in your dog’s system, it is crucial to give the medication as prescribed by your veterinarian and at the same time each day. Try hiding the chewable tablet in a treat or a tiny piece of food if your dog is having trouble swallowing it to make it more appealing.

Potential Side Effects of Deramaxx

Gastrointestinal problems: Some dogs may have vomiting, diarrhea, and decreased appetite.

Lethargy: While on Deramaxx, some dogs may become more lethargic or less energetic.

Skin reactions: Rarely, rashes, redness, or itching may appear.

The medication may also result in liver damage or anemia, low platelets, a faster breathing rate, a slower heartbeat, a cough, fever, swelling of the face, hives, or dermatitis.

Your pet may experience urinary system issues such as increased drinking and urination, blood in the urine, incontinence, nitrogen (the presence of nitrogen in the blood), or renal issues.

The negative events mentioned above have occasionally been reported to result in death. Consult your veterinarian if you think your pet might be experiencing any negative effects.

What to Discuss With Your Veterinarian Before Giving Deramaxx Tablets?

  1. Any negative effects that Deramaxx or other NSAIDs have had on your dog
  2. Any gastrointestinal distress (vomiting or diarrhea) your dog has experienced.
  3. Any kidney conditions that your dog has had.
  4. Any additional health issues or allergies your dog is currently experiencing or has had in the past.
  5. All medicines you are providing your dog or intend to give him, including over-the-counter medicines and any nutritional supplements.
  6. If your dog is pregnant or nursing, or if you intend to breed your dog.
  7. The significance of exercise, physical therapy, and weight management in the treatment of osteoarthritis.
  8. How frequently your dog may need to visit your veterinarian for monitoring.
  9. The advantages and disadvantages of Deramaxx tablets

What Dogs Should Not Take Deramaxx Tablets?

Your dog should not take Deramaxx tablets if;

  • Has experienced an allergic reaction (such as hives, facial swelling, or redness) to deracoxib, the active ingredient in DERAMAXX tablets
  • Is currently taking aspirin, other NSAIDs, or corticosteroids (unless your veterinarian instructs you otherwise), or has a reaction (such as hives or itching skin) to them
  • Has bloody stools or vomit; 
  • Has a kidney or liver disease 
  • Is anorexic (loses appetite).

Alternative to Deramaxx for dogs

There are various options available if your dog is unable to handle Deramaxx or if you need another more affordable option. These alternatives include, among others:

Carprofen (Rimadyl): This is a well-known NSAID used to relieve pain and inflammation in dogs 

Meloxicam (Metacam): This is a liquid nonsteroidal anti-inflammatory drug (NSAID) that is frequently prescribed for arthritis and other painful disorders.

Firocoxib (Previcox): this NSAID may be an option with anti-inflammatory effects similar to those of Deramaxx and is helpful for dogs with digestive sensitivity.

What Is The Best Natural Remedy For Arthritis In Dogs?

There are several all-natural treatments available for canine arthritis. While some are better than others, it’s crucial to discuss which choice could be best for your pet with your veterinarian.

Omega 3 fatty acids

Dogs with arthritis benefit greatly from omega-3 fatty acids. Through their capacity to lower oxidative stress in the body, which damages cells, and inflammation, omega-3 fatty acids enhance joint function. Omega 3 fatty acids are crucial for the heart, skin, hair, and brain, thus it’s critical to provide enough of them in the diet.


Boswellia is a herb that has been utilized for its medicinal properties for thousands of years. It has boswellic acid, an anti-inflammatory compound that can help lessen the discomfort and swelling brought on by arthritis. It functions well both alone and in combination with other herbs or supplements, such as turmeric (curcumin).

Hemp chews

Hemp seeds, which are high in omega-3 fatty acids, protein, and antioxidants, are used to make hemp chew snacks. These nutrients enhance joint health and reduce inflammation in dogs with arthritis by replenishing the cartilage tissue.


Turmeric contains the natural anti-inflammatory compound curcumin. Research indicates that turmeric, which has been used for medicinal purposes since ancient times, can be an effective treatment for arthritis in both people and dogs. Additionally, it’s fantastic for preserving good gut flora and promoting digestive wellness.

Chondroitin sulfate and glucosamine

Two of the most common supplements for arthritis, particularly in older dogs, are glucosamine and chondroitin sulfate. They are organic substances that may be found in cartilage, which is the material that keeps your joints healthy. These two supplements are frequently combined because they lessen arthritis-related inflammation and discomfort by acting in unison.

CBD oil

For years, people and pets have utilized CBD oil as a natural therapy to alleviate arthritis. It has a substance called cannabidiol (CBD) that may be able to reduce joint discomfort and inflammation in your pet. Since CBD oil is not psychoactive, it won’t have an impact on your dog’s emotions or behavior.

Deramaxx® Overdose Information

Overdoses of this medicine have been associated with decreased appetite, vomiting, dark tarry stools, and lethargy. Depending on how serious the overdose was, more severe symptoms may manifest.

Contact your veterinarian, seek emergency veterinary treatment, or get in touch with an animal poison control hotline immediately if you suspect an overdose.  

Pet Poison Helpline (855) 764-7661

ASPCA Animal Poison Control  (888) 426-4435      

Interactions With Other Drugs

NSAIDs shouldn’t be taken with corticosteroid medications like dexamethasone and prednisone.

It is especially crucial to carry out the necessary liver monitoring when Deramaxx and phenobarbital are both being administered simultaneously. (It is advised that dogs taking phenobarbital undergo bile acid testing every six months.) In the presence of Deramaxx, ACE inhibitors like enalapril or captopril might not work as well.

Does Deramaxx® make dogs sleepy?

Deramaxx® does not a dog sleepy. Lethargy may be a minor side effect of this medication, but if your pet appears to be very lethargic or you notice any other unusual symptoms while your pet is taking this medication, call an animal poison control center or immediately visit your veterinarian.


How can I tell if Deramaxx is working for my dog?

Your dog’s mobility may increase, their level of pain or discomfort may be lessened, and their general quality of life may be improved when Deramaxx is working as it should. To make sure the medication is functioning as intended and to make any required changes to the treatment plan, it is crucial to keep in touch with your vet and offer updates on your dog’s progress.

Can I abruptly stop providing Deramaxx to my dog?

Deramaxx should not be stopped abruptly without first talking to your veterinarian. Your veterinarian could advise gradually lowering the dosage before entirely ceasing treatment, depending on the condition being treated and the length of use. This strategy can reduce the possibility of unwanted consequences or a quick recurrence of inflammation and pain.

Can Deramaxx be given to puppies?

In general, Deramaxx is not advised for puppies younger than four months old. Young puppies may be particularly vulnerable to negative effects from NSAIDs like Deramaxx because of their maturing immunological and gastrointestinal systems. Consult your veterinarian for the best options if your puppy has to be treated for discomfort or inflammation.

What is the correct dosage of Deramaxx for my dog?

Depending on the disease being treated and your dog’s weight, the recommended dosage of Deramaxx will vary. Typically, 1-2 mg per pound of body weight, given once daily, is the suggested dosage. Following your veterinarian’s advice is crucial since they might change the dosage based on your dog’s individual needs.

Deramaxx Storage

According to the pharmaceutical label, Deramaxx® should be kept in a controlled environment between 59 and 86 degrees Fahrenheit. To safeguard this drug from moisture and light, keep the container completely closed.

Keep out of children’s and pets’ reach.

Can I give my dog human pain medications instead of Deramaxx?

No, aspirin, ibuprofen, or acetaminophen should never be administered to your dog as they are poisonous and may even be lethal to them. In addition to causing blood problems or central nervous system depression, these drugs can harm the gastrointestinal tract, the liver, or the kidneys. Your dog should only be administered drugs specifically approved for use in dogs, such as Deramaxx, and only when advised to do so by a veterinarian.

How can the possibility of Deramaxx side effects in my dog be reduced?

You must carefully adhere to your veterinarian’s dose and administration recommendations if you want to reduce the possibility of Deramaxx side effects in your dog. Deramaxx should not be administered to a dog that is sensitive to NSAIDs, has a history of GI bleeding or ulcers, or has kidney or liver problems. Deramaxx should not be given to dogs that are expecting or nursing unless specifically instructed to do so by your veterinarian. Your veterinarian should be informed of any unexpected symptoms or behaviors, as well as the way your dog is responding to the medication.

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