Previcox (firocoxib) Killed My Dog

All dogs are at risk of getting joint problems at some point in their life. Many dog owners discuss the type of medication, supplements, and type of food that they give to their dogs to cope with this condition when they are together. So, you might have heard that your friend’s dog had osteoarthritis-related pain and inflammation and Previcox worked wonders for him. Unfortunately, when your dog got the same problem and you went ahead and gave him the medication things turned sour.

It is very unfortunate that you lost your dog while trying to find ways of relieving his pain. Receive my heartfelt condolences. If you have found yourself blaming Previcox for your loss, this article is for you.

This article will discuss everything you need to know about Previcox, its side effects, alternatives, and more.

Previcox (firocoxib) Killed My Dog

It’s not necessarily true that Previcox killed your dog just because he had a bad reaction to it. If your dog died after using Previcox, there may have been underlying medical issues, drug interactions, an allergic reaction, or an overdose. Therefore, before giving your dog a Previcox treatment, make sure your veterinarian is aware of their overall condition. Additionally, discuss any potential Previcox side effects with your veterinarian.

What is Previcox?

Previcox is a non-steroidal anti-inflammatory (NSAID) medicine that has been approved by the FDA for use on prescription in dogs to treat osteoarthritis-related pain and inflammation as well as post-operative pain and inflammation brought on by orthopedic surgery. Before the procedure, your veterinarian may administer PREVICOX and may advise continuing treatment for the dog for a few days after returning home.

Like other drugs in its class, it can be used off-label to treat inflammation and fever brought on by various health issues. Off- or extra-label use refers to the use of a medication in a situation or on a specific species that is not authorized by the medication label. Although vets frequently prescribe drugs for off-label uses, your veterinarian will decide whether this drug is safe for your dog.

How Previcox Works

Previcox® is a type of selective NSAID with the COX-2 inhibitor subclass. Like other NSAIDs, it works by blocking the body’s COX-2 pathway to reduce the production of the natural chemicals that cause inflammation, lowering temperature, and reducing pain.

Previcox® usually spares the COX-1 pathway, which is linked to digestion, renal health, and blood clotting, as a result of its selectivity for the COX-2 route. This selectivity is advantageous because it has fewer negative effects than typical NSAIDs. It’s crucial to remember that Previcox® can still partially block these helpful compounds at large doses, therefore it’s crucial to adhere to your veterinarian’s instructions to the end.

What is Previcox Used for in Dogs?

Previcox is prescribed for dogs to treat medical conditions that cause discomfort and inflammation. Previcox is most frequently prescribed for dogs with joint problems. However, it can be used for other problems too. Here is a summary of the diseases for which Previcox for dogs is useful.


All dogs will have inflammation of the joints. Arthritis in dogs manifests itself as severe joint pain, stiffness, and a loss of mobility, unfortunately, it cannot be cured, only managed. Previcox does a great job of managing this condition.

Postoperative Pain

Previcox is normally prescribed both before and after surgical procedures since it offers reliable pain relief. Previcox is an effective pain reliever for both orthopedic and soft tissue surgeries.

Cancer Pain

Previcox is moreover used off-label to relieve discomfort in dogs who have certain cancers, such as transitional cell carcinoma. Small-breed dogs are more likely to develop transitional cell carcinoma, which mostly occurs in the bladder and urethra.

How do you handle a dog that died from Previcox?

The first thing you should do is autopsy your dog.

This may be a challenging task at first, but it will allow you to pinpoint the precise causes of their tragic passing.

Health issues or hazardous exposures are sometimes cited as additional causes of death.

You can take action if Previcox was the primary cause of the problem.

You could file a complaint with all supporting documentation, such as your dog’s medical history and all incidents leading up to his death if your dog passed away as a result of a drug product.

For more details on how to report severe medication reactions, visit the FDA website.

What are the Side Effects of Previcox for Dogs?

There could be several negative effects of this chewable tablet. Previcox’s common side effects are as follows:

  • Kidney problems
  • Nausea
  • Decreased food appetite due to liver problems
  • Jaundice
  • Unexpected weight loss
  • Yellowing of skin and eyes
  • Change in bowel movements
  • Change in drinking or urination habits
  • Red skin, scabs, or itchiness
  • Unexpected weight loss
  • Black, tarry, or bloody stools
  • Increased or decreased activity levels
  • Lack of coordination

If your dog exhibits any of the above symptoms after taking Previcox, stop administering it and contact your vet immediately.

Which dogs should not take PREVICOX?

Previcox therapy cannot be administered to your dog due to the high risk of serious side effects if;

  • your dog is allergic to the main ingredient
  • is below seven months
  • is taking other nephrotoxic drugs
  • is receiving concomitant diuretic therapy
  • is taking drugs that can cause interaction
  • If the dog is dehydrated, weak, or old.

Previcox, on the other hand, can be used with care and under close observation in the following situations:

  • dogs receiving supplementary therapy with other painkillers
  • dogs with stomach ulcers
  • dogs with inherited and acquired bleeding problems
  • dogs with liver and kidney disease
  • dogs with low blood pressure and heart problems

Previcox chewable pills have not been adequately studied for their effects or safety during breeding, pregnancy, or lactating in dogs. Previcox should not be used in these circumstances to prevent side effects.

Previcox for Dogs Dosage 

Previcox for dogs should be administered once daily at a dose of 2.27 mg/lb (5.0 mg/kg). The appropriate dosage will be decided by the veterinarian based on the dog’s body weight and the underlying problem.

It is advisable to give this medication with food to avoid stomach problems.

Be aware that there are two different strengths available: 57 mg and 227 mg. Consider a situation where a pet owner is administering Previcox to several dogs at once at various dosages. In this situation, the owner should be keen and acknowledge this variation in tablet strength.

The dosage is shown in the table below according to their website:

Dog Weight RangeTablet StrengthNumbers of Tablets/Day
12.5-18 pounds57mg tablet0.5 (one half of one tablet)
19-35 pounds57mg tablet1 tablet (one tablet)
36-71 pounds227mg tablet0.5 (one half of one tablet)
72-120 pounds227mg tablet1 tablet (one tablet)
121-160 pounds227mg tablet1.5 tablets (one and a half tablets)
161-240 pounds227mg tablet2 tablets (two tablets)


Depending on your dog’s special needs, any other medications they may be on, or the condition that initially led to the prescription for this medication, your vet may advise specific monitoring or regular testing while your dog is taking Previcox.

Veterinarians may advise stopping Previcox and looking for alternative therapies if your dog exhibits adverse effects or doesn’t improve.

Previcox Overdose Information

The following are often the warning indications of a Previcox overdose:

  • Tarry or bloody stool
  • Lethargy and decreased activity levels
  • Increased water intake
  • Increase urination frequency 
  • Pale or yellow gums
  • Jaundice and yellowing of the skin
  • Fast or heavy breathing
  • Incoordination and seizures 
  • Behavior changes.   

Contact your veterinarian, seek emergency veterinary treatment, or get in touch with an animal poison control hotline immediately if you suspect an overdose.

Pet Poison Helpline (855) 764-7661

ASPCA Animal Poison Control (888) 426-4435

How Long Does Previcox Stay in the Dog’s System?

Previcox remains in the dog’s system for several days after administration. But it takes around 8 hours for it to be eliminated. However, health issues such as kidney and liver problems may have an impact on how long this medication stays in the dog’s system.

How Long does it Take for Previcox for Dogs to Work?

Previcox is a fast-acting drug that begins to work shortly after being taken. Typically, it takes one to two hours. The initial dose will be followed by a noticeable improvement.

Drug Interactions with Previcox for Dogs

Drug interactions are a possibility with all medicines. When Previcox for dogs is taken concurrently with several different medications, there can be a drug interaction. These medications are listed below:

  • Other non-steroidal anti-inflammatory drugs 
  • Corticosteroids (Cortisone, Dexamethasone, Prednisone) 
  • Certain anesthetic drugs (intravenous and gaseous)
  • Protein-bound drugs (Phenytoin, Valproic acid)
  • ACE inhibitors and some heart medications (Digoxin)
  • Antifungals (Fluconazole), Diuretics (Furosemide), 
  • Anticoagulant drugs (Warfarin)
  • Chemotherapy agents (Methotrexate). 

To be on the safe side, you should let the vet know whether the dog is receiving any additional medications, such as vitamins, supplements, or herbal medicines. Talk about monitoring as well.

Alternatives for Previcox for Dogs

One of the most well-known painkillers and anti-inflammatory drugs is Previcox for dogs. But if it’s not the best option for your dog, discuss various alternatives with the vet. Here are a few well-liked dog Previcox substitutes.

Other NSAIDs for Dogs

The non-steroidal anti-inflammatory medicine (NSAID) class of medications includes various canine-friendly members, such as Rimadyl (Carprofen), Metacam (Meloxicam), Etogesic (Etodolac), and Deramaxx (Deracoxib). Every NSAID functions similarly and provides comparable amounts of pain and inflammation control. However, different dogs react to them in various ways. Additionally, avoid human-made medications like aspirin and ibuprofen.  

Tramadol for Dogs

These medications are artificial opioids. They are used to treat inflammation-related pain. Tramadol must, however, be administered again eight to twelve hours later. However, this medication can be taken in conjunction with other painkillers.

CBD Oil for Dogs

These are medications for pain relief that are made naturally. Oil and sweets are included in their ingredients. Additionally, Cannabinoid products have a sweet taste and help in strengthening the immune system.

Joint Supplements for Dogs

Your dog’s physician might occasionally suggest joint supplements. However, the veterinarian could recommend these supplements in addition to painkillers.

This is dependent on the dog’s health. These dietary supplements are made using substances like fish oil, vitamin C, glucosamine HCL, and manganese gluconate.

After ingesting these supplements, some dogs show changes fast. 

It would be preferable to speak with your veterinarian about the next supplement dosage. By doing this, you can protect your dogs from recurrent muscular-skeletal inflammation.


This spice is believed to have anti-inflammatory and pain-relieving effects. To treat pain and inflammation naturally, it can be given to dogs as a supplement or mixed into their diet.

Do I need a prescription for Previcox? 

Previcox is a COX-2 NSAID (non-steroidal anti-inflammatory drug) that is used to treat osteoarthritis-related pain and inflammation.

For this medication requires prior diagnosis and veterinary authorization before use.

Should you sue a vet if this occurs?

It’s a wise decision to seek justice for the loss of your cherished pet, but there are several things you should be aware of before deciding to sue your veterinarian.

It can be difficult to obtain just compensation when suing a veterinarian for misconduct.

There are a few competent attorneys out there who might be up for the task, especially if you have evidence to support the position you hold in court. While some attorneys might be reluctant to handle this type of case, some might be willing.

Compensations may vary depending on local laws and special situations that can make a persuasive case for receiving fair compensation.

If there is solid evidence that your dog died as a result of the medication or treatment there is a high chance of you winning the case.

A contingency fee, which refers to collecting a portion of the cash you receive if you win the case, is usually requested by attorneys who take on these matters.

Consider a scenario in which the settlement does not appear to be worth the expense of engaging your attorney. There are various other options available to you in that situation.

These include filing a simple negligence lawsuit, appealing to a small claims court, receiving an insurance settlement, and filing a complaint.


Can I crush or break the Previcox tablets for my dog?

Previcox tablets should not be crushed or broken; doing so could reduce the medication’s effectiveness. Instead, they should be administered whole. If your dog has difficulties swallowing the tablets, you can try concealing them in some food or giving them the medicine in a pill pocket to help them.

How should I store Previcox tablets for my dog?

Tablets of Previcox should be kept at room temperature, away from moisture, and in the shade. Until it’s time to give the tablets to your dog, keep them in their original package. Make sure that children and pets cannot access the medication.

How can I tell if Previcox is working for my dog?

It will take some time before the medicine show full effect but you will notice signs that your dog’s pain is decreasing. If you don’t notice any changes after your dog has taken the drug, it is advisable to talk to your vet.

Your vet can change the medication, adjust the dosage, or do more diagnostic tests.

How do I safely dispose of unused or expired Previcox tablets?

Your veterinary will advise you on the best way to dispose of the expired or unused Previcox. You can also follow the guidelines provided by your local disposal agent. It is not advisable to flush any medication down the toilet or throw it in the household trash because it can contribute to environmental contamination or harm wildlife.

Leave a Comment